After similarities to the Obama-era edition were picked up online, the text was revised to describe it as a "Federal Trade Commission booklet, promoted by First Lady Melania Trump".
Launching the "Be Best" initiative at the White House on Monday, Mrs Trump said the aim was to promote healthy living, encourage positive use of social media, and combat opioid abuse.
"As we all know, social media can both positively and negatively affect our children, but too often it is used in negative ways," she said.
Her decision to focus on cyberbullying has prompted questions about the behaviour of her husband, who frequently uses Twitter to attack and insult his opponents.
Mr Trump was widely criticised in 2017 when he used the platform to call TV hosts Mika Brzezinski and Joe Scarborough "low I.Q. Crazy Mika" and "Psycho Joe", and claimed he saw Ms Brzezinski "bleeding badly from a face-lift".
Asked whether Pres. Trump believes he has any responsibility for need to speak out against cyberbullying, Press Sec. Sanders says, "I think the idea that you're trying to blame cyberbullying on the president is kind of ridiculous." https://t.co/NkJuIoh4fPpic.twitter.com/ggeFzSd7Sg