ET caught up with the close pals at the Cannes Film Festival, whe-re they're promoting their film "Money Monster" -- out May 13 -- and Roberts dished on how Clooney has changed since settling down with the glamorous 38-year-old human rights lawyer.
"Our lives have expanded, though in a beautiful way," Roberts, 48, told ET about what it's like working with Clooney again since 2004's "Ocean's 12." The Oscarwinner acknowledged that marriage specifically has changed the dapper 55-year-old actor.
"Only when we're at their house I see the influence," she added, referring to her and her husband, cameraman Danny Moder, spending time with the Clooneys. "In a beautiful way that all wives kind of have a beautiful, loving influence over their husbands."
The former ER star, of course, agreed.
"I would concur because there is no version that I could not concur," Clooney joked. "I would get into trouble."
The longtime friends also dished to ET about their plans for a fun double date at Cannes -- though it all depends on Roberts.
"If Julia doesn't get too drunk, too early," Clooney cracked. "You know that happens ... happy hour somewhe-re."
On a more serious note, the A-listers explained their reputations for being on-set pranksters.
"Well, I mean, look -- I think after all these years, we both understand that we are lucky enough to have careers and have a job doing something that we love, so, I think it's really selfish if it's not fun for everybody," Clooney smiled.
And Clooney is definitely currently having the time of his life. He married Amal in September 2014, and by all appearances, is still just as smitten with his fashionable wife as ever.
"I've never been happier in a relationship by any stretch of the imagination," Clooney gushed to Esquire last month. "At 52 I found the love of my life and I'm really happy."
Last May, the once notorious bachelor revealed to ET why he fell in love with Amal.
"She's an amazing human being," he told ET's Nancy O'Dell. "And she's caring. And she also happens to be one of the smartest people I've ever met. And she's got a great sense of humor. There's a number of reasons why."